Tefé is a town in Amazonas, Brazil. It is about 525 km by air or 595 km by river to the west of Manaus on the south bank of the Solimões River (the upper Amazon), on the lake formed by the mouth of the Tefé River. It had a population of 87,000 in 2020. Tefé is the major starting point for trips into the Mamiraua Reserve.
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